Research across borders

Worldwide Study Finder

Where are peptides being studied? Explore registered human studies by product, phase, condition and location — from early development through Phase 4, alongside studies where phase does not apply.

Searchable results come from ClinicalTrials.gov and include international sites. For broader coverage, use the worldwide and regional registries below. No single registry captures every study.

Find studies Explore world registries Peptide directory

Find a study

Enter a peptide, product, condition or location. Try generic names, brand names and development codes separately. Results are registry search matches, not automatically verified links to a WPF peptide record.

Search terms are sent to ClinicalTrials.gov and appear in the page URL. Do not enter personal or medical identifying information. Registry records are served with up to a one-hour cache; registry updates themselves can lag real-world changes.

Registry search results

36 matching registry records; showing 20 on this page, newest registry updates first. Search checked 2026-11-08 17:29 UTC. Counts are registry matches, not unique peptides or a worldwide total.

Phase 2CompletedINTERVENTIONAL

Prolonged Pulsatile Kisspeptin Administration in Hypogonadotropic Hypogonadism

ClinicalTrials.gov · NCT04648969 · Registry updated: 2026-08-26

Condition / research focus: Hypogonadotropic Hypogonadism
Sponsor: Stephanie B. Seminara, MD
Countries with listed sites: United States
Registry dates and results: Start: 2019-05-03. Completion: 2025-08-31 (may be estimated). Results are posted in this registry.

Products and interventions (2)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

kisspeptin 112-121 (drug) — also listed as: metastin 45-54
GnRH (drug) — also listed as: gonadotropin-releasing hormone

Where the study takes place — 1 listed sites

Site status can differ from overall study status. This list includes all reported sites, even when your search specifies one location. Confirm availability and eligibility with the study team through the original record.

Massachusetts General Hospital
Boston, Massachusetts, United States
Site recruitment: Not reported

Original record, eligibility, contacts and results →

Phase 1RecruitingINTERVENTIONAL

Kisspeptin to Quantify GnRH Neuronal Function in Health and Disease

ClinicalTrials.gov · NCT07224490 · Registry updated: 2026-07-13

Condition / research focus: Reproductive Disorder; Neurodegeneration; SARS-CoV 2; Long COVID
Sponsor: Stephanie B. Seminara, MD
Countries with listed sites: United States
Registry dates and results: Start: 2026-03-10. Completion: 2030-05 (may be estimated). No results posted in this registry response.

Products and interventions (1)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

Kisspeptin 112-121 (drug) — also listed as: Metastin 45-54

Where the study takes place — 1 listed sites

Massachusetts General Hospital
Boston, Massachusetts, United States
Site recruitment: Recruiting

Original record, eligibility, contacts and results →

Phase not reported / not applicableCompletedOBSERVATIONAL

The Molecular Basis of Inherited Reproductive Disorders

ClinicalTrials.gov · NCT05971836 · Registry updated: 2026-07-13

Condition / research focus: Hypogonadotropic Hypogonadism; Reproductive Disorder; Kallmann Syndrome; Delayed Puberty
Sponsor: Stephanie B. Seminara, MD
Countries with listed sites: United States
Registry dates and results: Start: 2021-01-21. Completion: 2026-03-31 (may be estimated). No results posted in this registry response.

Products and interventions (0)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

Where the study takes place — 1 listed sites

Massachusetts General Hospital
Boston, Massachusetts, United States
Site recruitment: Not reported

Original record, eligibility, contacts and results →

Phase 2RecruitingINTERVENTIONAL

Kisspeptin Administration Subcutaneously to Patients With IHH

ClinicalTrials.gov · NCT05896293 · Registry updated: 2026-07-13

Condition / research focus: Hypogonadotropic Hypogonadism
Sponsor: Stephanie B. Seminara, MD
Countries with listed sites: United States
Registry dates and results: Start: 2023-02-03. Completion: 2028-05 (may be estimated). No results posted in this registry response.

Products and interventions (2)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

kisspeptin 112-121 (drug) — also listed as: metastin 45-54
leuprolide acetate (drug)

Where the study takes place — 1 listed sites

Massachusetts General Hospital
Boston, Massachusetts, United States
Site recruitment: Recruiting

Original record, eligibility, contacts and results →

Phase 2RecruitingINTERVENTIONAL

Kisspeptin Administration Subcutaneously to Patients With Hypothalamic Amenorrhea

ClinicalTrials.gov · NCT07224438 · Registry updated: 2026-07-13

Condition / research focus: Hypothalamic Amenorrhea; Hypogonadotropic Hypogonadism
Sponsor: Stephanie B. Seminara, MD
Countries with listed sites: United States
Registry dates and results: Start: 2025-12-09. Completion: 2030-05 (may be estimated). No results posted in this registry response.

Products and interventions (1)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

kisspeptin 112-121 (drug) — also listed as: Metastin 45-54

Where the study takes place — 1 listed sites

Massachusetts General Hospital
Boston, Massachusetts, United States
Site recruitment: Recruiting

Original record, eligibility, contacts and results →

Not applicableCompletedINTERVENTIONAL

Kissing as a Protective Factor Against Acidic pH in Saliva

ClinicalTrials.gov · NCT06501729 · Registry updated: 2026-04-24

Condition / research focus: Dental Caries; Tooth Demineralization; Teeth Erosion Limited to the Enamel
Sponsor: Universidad Catolica Santiago de Guayaquil
Countries with listed sites: Ecuador
Registry dates and results: Start: 2024-07-30. Completion: 2025-11-20 (may be estimated). No results posted in this registry response.

Products and interventions (1)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

Kiss (other)

Where the study takes place — 1 listed sites

School of Dentistry of the Catholic University Santiago de Guayaquil
Guayaquil, Guayas, Ecuador
Site recruitment: Not reported

Original record, eligibility, contacts and results →

Phase not reported / not applicableRecruitingOBSERVATIONAL

Functional Proteins in Polycystic Ovary Syndrome

ClinicalTrials.gov · NCT06793098 · Registry updated: 2026-03-18

Condition / research focus: Reproductive Age; PCOS (Polycystic Ovary Syndrome)
Sponsor: Jagiellonian University
Countries with listed sites: Poland
Registry dates and results: Start: 2025-01-20. Completion: 2027-12-31 (may be estimated). No results posted in this registry response.

Products and interventions (3)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

Measurement of kisspeptin concentration (diagnostic_test)
Measurement of ghrelin concentration (diagnostic_test)
Measurement of zonulin concentration (diagnostic_test)

Where the study takes place — 1 listed sites

Jagiellonian University
Krakow, Poland
Site recruitment: Recruiting

Original record, eligibility, contacts and results →

Phase 1TerminatedINTERVENTIONAL

Recall by Genotype: Neuropeptide Stimulation

ClinicalTrials.gov · NCT05901467 · Registry updated: 2026-03-06

Condition / research focus: Reproductive Disorder
Sponsor: Stephanie B. Seminara, MD
Countries with listed sites: United States
Registry dates and results: Start: 2023-10-20. Completion: 2024-05-29 (may be estimated). Results are posted in this registry.

Products and interventions (2)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

kisspeptin 112-121 (drug) — also listed as: metastin 45-54
GnRH (drug) — also listed as: gonadotropin-releasing hormone

Where the study takes place — 1 listed sites

Massachusetts General Hospital
Boston, Massachusetts, United States
Site recruitment: Not reported

Original record, eligibility, contacts and results →

Phase 1CompletedINTERVENTIONAL

Evaluation of Kisspeptin Glucose-Stimulated Insulin Secretion With Oral Glucose Tolerance Test

ClinicalTrials.gov · NCT04958109 · Registry updated: 2026-03-06

Condition / research focus: Metabolic Diseases
Sponsor: Massachusetts General Hospital
Countries with listed sites: United States
Registry dates and results: Start: 2021-10-28. Completion: 2022-10-31 (may be estimated). Results are posted in this registry.

Products and interventions (3)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

Oral Glucose Tolerance Test (diagnostic_test)
Kisspeptin (drug)
Placebo (drug)

Where the study takes place — 1 listed sites

Massachusetts General Hospital
Boston, Massachusetts, United States
Site recruitment: Not reported

Original record, eligibility, contacts and results →

Phase not reported / not applicableCompletedOBSERVATIONAL

Detection of Kisspeptins and miRNAs in Patients With Non-viable Pregnancy

ClinicalTrials.gov · NCT03877939 · Registry updated: 2026-01-13

Condition / research focus: Non-Viable Pregnancy
Sponsor: Vida Recoletas Sevilla
Countries with listed sites: Spain
Registry dates and results: Start: 2019-09-15. Completion: 2025-03-20 (may be estimated). No results posted in this registry response.

Products and interventions (1)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

Blood samples collection for analysis (diagnostic_test) — also listed as: Uterine biopsy sample collection (only in biochemical pregnancy patients)

Where the study takes place — 2 listed sites

IVI RMA Madrid
Madrid, Madrid, Spain
Site recruitment: Not reported
IVI RMA Seville
Seville, Seville, Spain
Site recruitment: Not reported

Original record, eligibility, contacts and results →

Phase 1CompletedINTERVENTIONAL

Dampening the Reproductive Axis With Continuous Kisspeptin

ClinicalTrials.gov · NCT05971849 · Registry updated: 2025-11-05

Condition / research focus: Reproductive Disorder; PCOS; Polycystic Ovary Syndrome
Sponsor: Stephanie B. Seminara, MD
Countries with listed sites: United States
Registry dates and results: Start: 2023-10-06. Completion: 2024-04-27 (may be estimated). No results posted in this registry response.

Products and interventions (1)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

kisspeptin 112-121 (drug) — also listed as: metastin 45-54

Where the study takes place — 1 listed sites

Massachusetts General Hospital
Boston, Massachusetts, United States
Site recruitment: Not reported

Original record, eligibility, contacts and results →

Phase 1CompletedINTERVENTIONAL

Kisspeptin Administration Subcutaneously to Patients With Reproductive Disorders

ClinicalTrials.gov · NCT05633966 · Registry updated: 2025-10-03

Condition / research focus: Hypothalamic Amenorrhea; Hypogonadotropic Hypogonadism
Sponsor: Stephanie B. Seminara, MD
Countries with listed sites: United States
Registry dates and results: Start: 2022-12-16. Completion: 2025-08-31 (may be estimated). No results posted in this registry response.

Products and interventions (1)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

Kisspeptin 112-121 (drug) — also listed as: metastin 45-54

Where the study takes place — 1 listed sites

Massachusetts General Hospital
Boston, Massachusetts, United States
Site recruitment: Not reported

Original record, eligibility, contacts and results →

Phase not reported / not applicableCompletedOBSERVATIONAL

Molecules Associated with Pediatric Obesity

ClinicalTrials.gov · NCT06775990 · Registry updated: 2025-01-17

Condition / research focus: OBESITY
Sponsor: Istanbul University - Cerrahpasa
Countries with listed sites: Turkey (Türkiye)
Registry dates and results: Start: 2020-06-04. Completion: 2022-06-08 (may be estimated). No results posted in this registry response.

Products and interventions (1)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

Blood sample (other)

Where the study takes place — 1 listed sites

Namik Kemal University
Tekirdağ, Tekirdağ, Turkey (Türkiye)
Site recruitment: Not reported

Original record, eligibility, contacts and results →

Phase 2CompletedINTERVENTIONAL

Administration of Kisspeptin in Patients With Hyperprolactinemia

ClinicalTrials.gov · NCT02956447 · Registry updated: 2024-10-01

Condition / research focus: Hyperprolactinemia; Hypogonadism
Sponsor: Massachusetts General Hospital
Countries with listed sites: United States
Registry dates and results: Start: 2017-11-17. Completion: 2023-07-29 (may be estimated). Results are posted in this registry.

Products and interventions (2)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

Kisspeptin 112-121 (drug) — also listed as: Metastin 45-54
GnRH (drug) — also listed as: gonadotropin-releasing hormone

Where the study takes place — 1 listed sites

Massachusetts General Hospital
Boston, Massachusetts, United States
Site recruitment: Not reported

Original record, eligibility, contacts and results →

Not applicableRecruitingINTERVENTIONAL

Reproductive Hormones During Sustained Administration of Kisspeptin

ClinicalTrials.gov · NCT02081924 · Registry updated: 2024-09-19

Condition / research focus: Fertility Disorders; Hypothalamic Dysfunction
Sponsor: Imperial College London
Countries with listed sites: United Kingdom
Registry dates and results: Start: 2014-04-02. Completion: 2027-11-30 (may be estimated). No results posted in this registry response.

Products and interventions (4)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

Kisspeptin 0.1 (other)
Saline (other)
Kisspeptin 0.3 (other)
Kisspeptin 1.0 (other)

Where the study takes place — 1 listed sites

Imperial College NHS Healthcare Trust
London, United Kingdom
Site recruitment: Recruiting

Original record, eligibility, contacts and results →

Phase 1WithdrawnINTERVENTIONAL

Evaluation of Kisspeptin Stimulated Insulin Secretion With Hyperglycemic Clamp

ClinicalTrials.gov · NCT05456854 · Registry updated: 2024-08-14

Condition / research focus: Metabolic Disease
Sponsor: Massachusetts General Hospital
Countries with listed sites: United States
Registry dates and results: Start: 2022-06-03. Completion: 2024-08-01 (may be estimated). No results posted in this registry response.

Products and interventions (3)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

Hyperglycemic Clamp (diagnostic_test)
Kisspeptin-10 (drug)
Placebo (drug)

Where the study takes place — 1 listed sites

Massachusetts General Hospital
Boston, Massachusetts, United States
Site recruitment: Not reported

Original record, eligibility, contacts and results →

Phase not reported / not applicableUnknownOBSERVATIONAL

A Prospective Cohort Study on the Serum Kisspeptin Levels Throughout Pregnancy in PCOS

ClinicalTrials.gov · NCT06545994 · Registry updated: 2024-08-14

Condition / research focus: Polycystic Ovary Syndrome; Pregnancy Complications
Sponsor: Fudan University
Countries with listed sites: China
Registry dates and results: Start: 2024-06-28. Completion: 2026-06-30 (may be estimated). No results posted in this registry response.

Products and interventions (1)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

Observation (other)

Where the study takes place — 1 listed sites

OB & GYN Hospital of Fudan University
Shanghai, Shanghai Municipality, China
Site recruitment: Recruiting

Original record, eligibility, contacts and results →

Phase 1WithdrawnINTERVENTIONAL

Evaluation of Kisspeptin Glucose-Stimulated Insulin Secretion With Physiologic Mixed Meal Tolerance

ClinicalTrials.gov · NCT04532801 · Registry updated: 2024-08-01

Condition / research focus: Insulin; Glucose; Healthy Volunteers; Women; Pregnancy
Sponsor: Stephanie B. Seminara, MD
Countries with listed sites: United States
Registry dates and results: Start: 2019-09-01. Completion: 2024-12-21 (may be estimated). No results posted in this registry response.

Products and interventions (2)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

Kisspeptin-10 (drug) — also listed as: kisspeptin
mixed meal tolerance test (other)

Where the study takes place — 1 listed sites

Massachusetts General Hospital
Boston, Massachusetts, United States
Site recruitment: Not reported

Original record, eligibility, contacts and results →

Phase 1CompletedINTERVENTIONAL

Neuropeptides in Human Reproduction

ClinicalTrials.gov · NCT01952782 · Registry updated: 2024-07-31

Condition / research focus: Hypogonadotropic Hypogonadism
Sponsor: Massachusetts General Hospital
Countries with listed sites: United States
Registry dates and results: Start: 2014-04-30. Completion: 2016-05-31 (may be estimated). No results posted in this registry response.

Products and interventions (3)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

Kisspeptin 112-121 (drug) — also listed as: Metastin 45-54
Naloxone (drug)
GnRH (drug) — also listed as: Gonadotropin-releasing hormone

Where the study takes place — 1 listed sites

Massachusetts General Hospital
Boston, Massachusetts, United States
Site recruitment: Not reported

Original record, eligibility, contacts and results →

Phase 1CompletedINTERVENTIONAL

Kisspeptin Administration in the Adult

ClinicalTrials.gov · NCT00914823 · Registry updated: 2024-07-31

Condition / research focus: Hypogonadotropic Hypogonadism; Kallmann Syndrome; GnRH Deficiency; PCOS; Polycystic Ovarian Syndrome; Hyperprolactinemia
Sponsor: Massachusetts General Hospital
Countries with listed sites: United States
Registry dates and results: Start: 2009-06-23. Completion: 2021-10-22 (may be estimated). No results posted in this registry response.

Products and interventions (2)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

kisspeptin 112-121 (drug) — also listed as: metastin 45-54
GnRH (drug) — also listed as: gonadotropin-releasing hormone

Where the study takes place — 1 listed sites

Massachusetts General Hospital
Boston, Massachusetts, United States
Site recruitment: Not reported

Original record, eligibility, contacts and results →

Explore the world’s study registries

These links open external registries; their records are not merged into the results above. WHO ICTRP provides a broader search across contributing registries. Search the same generic name, aliases and development codes in relevant regions. One multinational study may appear in more than one registry, so compare registration identifiers before counting it twice.

Worldwide

Africa

Pan African Clinical Trial Registry ↗

Americas

Asia

Middle East

Europe

Oceania

Australia / New Zealand — ANZCTR ↗

Registry directory checked October 5, 2026 against the WHO registry network. This is a starting point, not complete coverage of every country or continent. Record availability, language and update schedules vary by registry.

Worldwide Study Finder

Loading registry information…

Worldwide Study Finder

Where are peptides being studied? Explore registered human studies by product, phase, condition and location — from early development through Phase 4, alongside studies where phase does not apply.

Searchable results come from ClinicalTrials.gov and include international sites. For broader coverage, use the worldwide and regional registries below. No single registry captures every study.

Find a study

Registry search results

36 matching registry records; showing 20 on this page, newest registry updates first. Search checked 2026-11-08 17:29 UTC. Counts are registry matches, not unique peptides or a worldwide total.

Phase 2CompletedINTERVENTIONAL

Prolonged Pulsatile Kisspeptin Administration in Hypogonadotropic Hypogonadism

ClinicalTrials.gov · NCT04648969 · Registry updated: 2026-08-26

Condition / research focus: Hypogonadotropic Hypogonadism
Sponsor: Stephanie B. Seminara, MD
Countries with listed sites: United States
Registry dates and results: Start: 2019-05-03. Completion: 2025-08-31 (may be estimated). Results are posted in this registry.

Products and interventions (2)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

kisspeptin 112-121 (drug) — also listed as: metastin 45-54
GnRH (drug) — also listed as: gonadotropin-releasing hormone

Where the study takes place — 1 listed sites

Massachusetts General Hospital
Boston, Massachusetts, United States
Site recruitment: Not reported

Original record, eligibility, contacts and results →

Phase 1RecruitingINTERVENTIONAL

Kisspeptin to Quantify GnRH Neuronal Function in Health and Disease

ClinicalTrials.gov · NCT07224490 · Registry updated: 2026-07-13

Condition / research focus: Reproductive Disorder; Neurodegeneration; SARS-CoV 2; Long COVID
Sponsor: Stephanie B. Seminara, MD
Countries with listed sites: United States
Registry dates and results: Start: 2026-03-10. Completion: 2030-05 (may be estimated). No results posted in this registry response.

Products and interventions (1)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

Kisspeptin 112-121 (drug) — also listed as: Metastin 45-54

Where the study takes place — 1 listed sites

Massachusetts General Hospital
Boston, Massachusetts, United States
Site recruitment: Recruiting

Original record, eligibility, contacts and results →

Phase not reported / not applicableCompletedOBSERVATIONAL

The Molecular Basis of Inherited Reproductive Disorders

ClinicalTrials.gov · NCT05971836 · Registry updated: 2026-07-13

Condition / research focus: Hypogonadotropic Hypogonadism; Reproductive Disorder; Kallmann Syndrome; Delayed Puberty
Sponsor: Stephanie B. Seminara, MD
Countries with listed sites: United States
Registry dates and results: Start: 2021-01-21. Completion: 2026-03-31 (may be estimated). No results posted in this registry response.

Products and interventions (0)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

Where the study takes place — 1 listed sites

Massachusetts General Hospital
Boston, Massachusetts, United States
Site recruitment: Not reported

Original record, eligibility, contacts and results →

Phase 2RecruitingINTERVENTIONAL

Kisspeptin Administration Subcutaneously to Patients With IHH

ClinicalTrials.gov · NCT05896293 · Registry updated: 2026-07-13

Condition / research focus: Hypogonadotropic Hypogonadism
Sponsor: Stephanie B. Seminara, MD
Countries with listed sites: United States
Registry dates and results: Start: 2023-02-03. Completion: 2028-05 (may be estimated). No results posted in this registry response.

Products and interventions (2)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

kisspeptin 112-121 (drug) — also listed as: metastin 45-54
leuprolide acetate (drug)

Where the study takes place — 1 listed sites

Massachusetts General Hospital
Boston, Massachusetts, United States
Site recruitment: Recruiting

Original record, eligibility, contacts and results →

Phase 2RecruitingINTERVENTIONAL

Kisspeptin Administration Subcutaneously to Patients With Hypothalamic Amenorrhea

ClinicalTrials.gov · NCT07224438 · Registry updated: 2026-07-13

Condition / research focus: Hypothalamic Amenorrhea; Hypogonadotropic Hypogonadism
Sponsor: Stephanie B. Seminara, MD
Countries with listed sites: United States
Registry dates and results: Start: 2025-12-09. Completion: 2030-05 (may be estimated). No results posted in this registry response.

Products and interventions (1)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

kisspeptin 112-121 (drug) — also listed as: Metastin 45-54

Where the study takes place — 1 listed sites

Massachusetts General Hospital
Boston, Massachusetts, United States
Site recruitment: Recruiting

Original record, eligibility, contacts and results →

Not applicableCompletedINTERVENTIONAL

Kissing as a Protective Factor Against Acidic pH in Saliva

ClinicalTrials.gov · NCT06501729 · Registry updated: 2026-04-24

Condition / research focus: Dental Caries; Tooth Demineralization; Teeth Erosion Limited to the Enamel
Sponsor: Universidad Catolica Santiago de Guayaquil
Countries with listed sites: Ecuador
Registry dates and results: Start: 2024-07-30. Completion: 2025-11-20 (may be estimated). No results posted in this registry response.

Products and interventions (1)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

Kiss (other)

Where the study takes place — 1 listed sites

School of Dentistry of the Catholic University Santiago de Guayaquil
Guayaquil, Guayas, Ecuador
Site recruitment: Not reported

Original record, eligibility, contacts and results →

Phase not reported / not applicableRecruitingOBSERVATIONAL

Functional Proteins in Polycystic Ovary Syndrome

ClinicalTrials.gov · NCT06793098 · Registry updated: 2026-03-18

Condition / research focus: Reproductive Age; PCOS (Polycystic Ovary Syndrome)
Sponsor: Jagiellonian University
Countries with listed sites: Poland
Registry dates and results: Start: 2025-01-20. Completion: 2027-12-31 (may be estimated). No results posted in this registry response.

Products and interventions (3)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

Measurement of kisspeptin concentration (diagnostic_test)
Measurement of ghrelin concentration (diagnostic_test)
Measurement of zonulin concentration (diagnostic_test)

Where the study takes place — 1 listed sites

Jagiellonian University
Krakow, Poland
Site recruitment: Recruiting

Original record, eligibility, contacts and results →

Phase 1TerminatedINTERVENTIONAL

Recall by Genotype: Neuropeptide Stimulation

ClinicalTrials.gov · NCT05901467 · Registry updated: 2026-03-06

Condition / research focus: Reproductive Disorder
Sponsor: Stephanie B. Seminara, MD
Countries with listed sites: United States
Registry dates and results: Start: 2023-10-20. Completion: 2024-05-29 (may be estimated). Results are posted in this registry.

Products and interventions (2)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

kisspeptin 112-121 (drug) — also listed as: metastin 45-54
GnRH (drug) — also listed as: gonadotropin-releasing hormone

Where the study takes place — 1 listed sites

Massachusetts General Hospital
Boston, Massachusetts, United States
Site recruitment: Not reported

Original record, eligibility, contacts and results →

Phase 1CompletedINTERVENTIONAL

Evaluation of Kisspeptin Glucose-Stimulated Insulin Secretion With Oral Glucose Tolerance Test

ClinicalTrials.gov · NCT04958109 · Registry updated: 2026-03-06

Condition / research focus: Metabolic Diseases
Sponsor: Massachusetts General Hospital
Countries with listed sites: United States
Registry dates and results: Start: 2021-10-28. Completion: 2022-10-31 (may be estimated). Results are posted in this registry.

Products and interventions (3)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

Oral Glucose Tolerance Test (diagnostic_test)
Kisspeptin (drug)
Placebo (drug)

Where the study takes place — 1 listed sites

Massachusetts General Hospital
Boston, Massachusetts, United States
Site recruitment: Not reported

Original record, eligibility, contacts and results →

Phase not reported / not applicableCompletedOBSERVATIONAL

Detection of Kisspeptins and miRNAs in Patients With Non-viable Pregnancy

ClinicalTrials.gov · NCT03877939 · Registry updated: 2026-01-13

Condition / research focus: Non-Viable Pregnancy
Sponsor: Vida Recoletas Sevilla
Countries with listed sites: Spain
Registry dates and results: Start: 2019-09-15. Completion: 2025-03-20 (may be estimated). No results posted in this registry response.

Products and interventions (1)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

Blood samples collection for analysis (diagnostic_test) — also listed as: Uterine biopsy sample collection (only in biochemical pregnancy patients)

Where the study takes place — 2 listed sites

IVI RMA Madrid
Madrid, Madrid, Spain
Site recruitment: Not reported
IVI RMA Seville
Seville, Seville, Spain
Site recruitment: Not reported

Original record, eligibility, contacts and results →

Phase 1CompletedINTERVENTIONAL

Dampening the Reproductive Axis With Continuous Kisspeptin

ClinicalTrials.gov · NCT05971849 · Registry updated: 2025-11-05

Condition / research focus: Reproductive Disorder; PCOS; Polycystic Ovary Syndrome
Sponsor: Stephanie B. Seminara, MD
Countries with listed sites: United States
Registry dates and results: Start: 2023-10-06. Completion: 2024-04-27 (may be estimated). No results posted in this registry response.

Products and interventions (1)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

kisspeptin 112-121 (drug) — also listed as: metastin 45-54

Where the study takes place — 1 listed sites

Massachusetts General Hospital
Boston, Massachusetts, United States
Site recruitment: Not reported

Original record, eligibility, contacts and results →

Phase 1CompletedINTERVENTIONAL

Kisspeptin Administration Subcutaneously to Patients With Reproductive Disorders

ClinicalTrials.gov · NCT05633966 · Registry updated: 2025-10-03

Condition / research focus: Hypothalamic Amenorrhea; Hypogonadotropic Hypogonadism
Sponsor: Stephanie B. Seminara, MD
Countries with listed sites: United States
Registry dates and results: Start: 2022-12-16. Completion: 2025-08-31 (may be estimated). No results posted in this registry response.

Products and interventions (1)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

Kisspeptin 112-121 (drug) — also listed as: metastin 45-54

Where the study takes place — 1 listed sites

Massachusetts General Hospital
Boston, Massachusetts, United States
Site recruitment: Not reported

Original record, eligibility, contacts and results →

Phase not reported / not applicableCompletedOBSERVATIONAL

Molecules Associated with Pediatric Obesity

ClinicalTrials.gov · NCT06775990 · Registry updated: 2025-01-17

Condition / research focus: OBESITY
Sponsor: Istanbul University - Cerrahpasa
Countries with listed sites: Turkey (Türkiye)
Registry dates and results: Start: 2020-06-04. Completion: 2022-06-08 (may be estimated). No results posted in this registry response.

Products and interventions (1)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

Blood sample (other)

Where the study takes place — 1 listed sites

Namik Kemal University
Tekirdağ, Tekirdağ, Turkey (Türkiye)
Site recruitment: Not reported

Original record, eligibility, contacts and results →

Phase 2CompletedINTERVENTIONAL

Administration of Kisspeptin in Patients With Hyperprolactinemia

ClinicalTrials.gov · NCT02956447 · Registry updated: 2024-10-01

Condition / research focus: Hyperprolactinemia; Hypogonadism
Sponsor: Massachusetts General Hospital
Countries with listed sites: United States
Registry dates and results: Start: 2017-11-17. Completion: 2023-07-29 (may be estimated). Results are posted in this registry.

Products and interventions (2)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

Kisspeptin 112-121 (drug) — also listed as: Metastin 45-54
GnRH (drug) — also listed as: gonadotropin-releasing hormone

Where the study takes place — 1 listed sites

Massachusetts General Hospital
Boston, Massachusetts, United States
Site recruitment: Not reported

Original record, eligibility, contacts and results →

Not applicableRecruitingINTERVENTIONAL

Reproductive Hormones During Sustained Administration of Kisspeptin

ClinicalTrials.gov · NCT02081924 · Registry updated: 2024-09-19

Condition / research focus: Fertility Disorders; Hypothalamic Dysfunction
Sponsor: Imperial College London
Countries with listed sites: United Kingdom
Registry dates and results: Start: 2014-04-02. Completion: 2027-11-30 (may be estimated). No results posted in this registry response.

Products and interventions (4)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

Kisspeptin 0.1 (other)
Saline (other)
Kisspeptin 0.3 (other)
Kisspeptin 1.0 (other)

Where the study takes place — 1 listed sites

Imperial College NHS Healthcare Trust
London, United Kingdom
Site recruitment: Recruiting

Original record, eligibility, contacts and results →

Phase 1WithdrawnINTERVENTIONAL

Evaluation of Kisspeptin Stimulated Insulin Secretion With Hyperglycemic Clamp

ClinicalTrials.gov · NCT05456854 · Registry updated: 2024-08-14

Condition / research focus: Metabolic Disease
Sponsor: Massachusetts General Hospital
Countries with listed sites: United States
Registry dates and results: Start: 2022-06-03. Completion: 2024-08-01 (may be estimated). No results posted in this registry response.

Products and interventions (3)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

Hyperglycemic Clamp (diagnostic_test)
Kisspeptin-10 (drug)
Placebo (drug)

Where the study takes place — 1 listed sites

Massachusetts General Hospital
Boston, Massachusetts, United States
Site recruitment: Not reported

Original record, eligibility, contacts and results →

Phase not reported / not applicableUnknownOBSERVATIONAL

A Prospective Cohort Study on the Serum Kisspeptin Levels Throughout Pregnancy in PCOS

ClinicalTrials.gov · NCT06545994 · Registry updated: 2024-08-14

Condition / research focus: Polycystic Ovary Syndrome; Pregnancy Complications
Sponsor: Fudan University
Countries with listed sites: China
Registry dates and results: Start: 2024-06-28. Completion: 2026-06-30 (may be estimated). No results posted in this registry response.

Products and interventions (1)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

Observation (other)

Where the study takes place — 1 listed sites

OB & GYN Hospital of Fudan University
Shanghai, Shanghai Municipality, China
Site recruitment: Recruiting

Original record, eligibility, contacts and results →

Phase 1WithdrawnINTERVENTIONAL

Evaluation of Kisspeptin Glucose-Stimulated Insulin Secretion With Physiologic Mixed Meal Tolerance

ClinicalTrials.gov · NCT04532801 · Registry updated: 2024-08-01

Condition / research focus: Insulin; Glucose; Healthy Volunteers; Women; Pregnancy
Sponsor: Stephanie B. Seminara, MD
Countries with listed sites: United States
Registry dates and results: Start: 2019-09-01. Completion: 2024-12-21 (may be estimated). No results posted in this registry response.

Products and interventions (2)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

Kisspeptin-10 (drug) — also listed as: kisspeptin
mixed meal tolerance test (other)

Where the study takes place — 1 listed sites

Massachusetts General Hospital
Boston, Massachusetts, United States
Site recruitment: Not reported

Original record, eligibility, contacts and results →

Phase 1CompletedINTERVENTIONAL

Neuropeptides in Human Reproduction

ClinicalTrials.gov · NCT01952782 · Registry updated: 2024-07-31

Condition / research focus: Hypogonadotropic Hypogonadism
Sponsor: Massachusetts General Hospital
Countries with listed sites: United States
Registry dates and results: Start: 2014-04-30. Completion: 2016-05-31 (may be estimated). No results posted in this registry response.

Products and interventions (3)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

Kisspeptin 112-121 (drug) — also listed as: Metastin 45-54
Naloxone (drug)
GnRH (drug) — also listed as: Gonadotropin-releasing hormone

Where the study takes place — 1 listed sites

Massachusetts General Hospital
Boston, Massachusetts, United States
Site recruitment: Not reported

Original record, eligibility, contacts and results →

Phase 1CompletedINTERVENTIONAL

Kisspeptin Administration in the Adult

ClinicalTrials.gov · NCT00914823 · Registry updated: 2024-07-31

Condition / research focus: Hypogonadotropic Hypogonadism; Kallmann Syndrome; GnRH Deficiency; PCOS; Polycystic Ovarian Syndrome; Hyperprolactinemia
Sponsor: Massachusetts General Hospital
Countries with listed sites: United States
Registry dates and results: Start: 2009-06-23. Completion: 2021-10-22 (may be estimated). No results posted in this registry response.

Products and interventions (2)

Includes comparators and combinations. A search match is not a verified peptide identity or evidence of benefit.

kisspeptin 112-121 (drug) — also listed as: metastin 45-54
GnRH (drug) — also listed as: gonadotropin-releasing hormone

Where the study takes place — 1 listed sites

Massachusetts General Hospital
Boston, Massachusetts, United States
Site recruitment: Not reported

Original record, eligibility, contacts and results →