Published peptide research references
Leuprolide
Governed registry record
25 approved source records with original-source links. Source verification confirms the reference and its connection to this record; it does not certify every scientific conclusion or establish safety or efficacy.
Open the peptide evidence profile →Approved source records
The Effect of Leuprolide Acetate 11.25 mg 3-Month Formulation in Children with Central Precocious Puberty: A Systematic Review and Meta-analysis.
Linqi Han, Chunjuan Zhai, La Da, Yan Sun · Advances in therapy · 2025
Effectiveness of leuprolide acetate administered monthly compared to three-monthly in the treatment of central precocious puberty: evaluation at the end of treatment.
Thanaporn Thaneetrakool, Suphab Aroonparkmongkol, Nattakarn Numsriskulrat, Vichit Supornsilchai, Suttipong Wacharasindhu, Khomsak Srilanchakon · Frontiers in endocrinology · 2024
Testosterone Recovery for Relugolix Versus Leuprolide in Men with Advanced Prostate Cancer: Results from the Phase 3 HERO Study.
Ronald Tutrone, Fred Saad, Daniel J George, Bertrand Tombal, James L Bailen, Michael S Cookson, Daniel R Saltzstein, Sarah Hanson, Bruce Brown, Sophia Lu, Mark Fallick, Neal D Shore · European urology oncology · 2024
Improved Outcomes with Enzalutamide in Biochemically Recurrent Prostate Cancer.
Stephen J Freedland, Murilo de Almeida Luz, Ugo De Giorgi, Martin Gleave, Geoffrey T Gotto, Christopher M Pieczonka, Gabriel P Haas, Choung-Soo Kim, Miguel Ramirez-Backhaus, Antti Rannikko, Jamal Tarazi, Swetha Sridharan · The New England journal of medicine · 2023
Cardiovascular Safety of Degarelix Versus Leuprolide in Patients With Prostate Cancer: The Primary Results of the PRONOUNCE Randomized Trial.
Renato D Lopes, Celestia S Higano, Susan F Slovin, Adam J Nelson, Robert Bigelow, Per S Sørensen, Chiara Melloni, Shaun G Goodman, Christopher P Evans, Jan Nilsson, Deepak L Bhatt, Noel W Clarke · Circulation · 2021
Oral Relugolix for Androgen-Deprivation Therapy in Advanced Prostate Cancer.
Neal D Shore, Fred Saad, Michael S Cookson, Daniel J George, Daniel R Saltzstein, Ronald Tutrone, Hideyuki Akaza, Alberto Bossi, David F van Veenhuyzen, Bryan Selby, Xiaolin Fan, Vicky Kang · The New England journal of medicine · 2020
A New Sustained-release, 3-Month Leuprolide Acetate Formulation Achieves and Maintains Castrate Concentrations of Testosterone in Patients With Prostate Cancer.
Neal D Shore, Sílvia Guerrero, Rosa Ma Sanahuja, Gemma Gambús, Antonio Parente · Clinical therapeutics · 2019
Are all gonadotrophin-releasing hormone agonists equivalent for the treatment of prostate cancer? A systematic review.
Eva M Bolton, Thomas Lynch · BJU international · 2018
FSH suppression and tumour control in patients with prostate cancer during androgen deprivation with a GnRH agonist or antagonist.
E David Crawford, B Tombal, T Keane, F Boccardo, K Miller, N Shore, J W Moul, J-E Damber, L Collette, B-E Persson · Scandinavian journal of urology · 2018
Monitoring treatment of central precocious puberty using basal luteinizing hormone levels and practical considerations for dosing with a 3-month leuprolide acetate formulation.
Peter A Lee, Margaret Luce, Peter Bacher · Journal of pediatric endocrinology & metabolism : JPEM · 2016
Gonadotropin and Estradiol Levels after Leuprolide Stimulation Tests in Brazilian Girls with Precocious Puberty.
Flavia R R Junqueira, Lucia A S Lara, Wellington P Martins, Rui A Ferriani, Ana Carolina J S Rosa-E-Silva, Marcos Felipe S de Sá, Rosana M Reis · Journal of pediatric and adolescent gynecology · 2015
Ulipristal acetate versus leuprolide acetate for uterine fibroids.
Jacques Donnez, Janusz Tomaszewski, Francisco Vázquez, Philippe Bouchard, Boguslav Lemieszczuk, Francesco Baró, Kazem Nouri, Luigi Selvaggi, Krzysztof Sodowski, Elke Bestel, Paul Terrill, Ian Osterloh · The New England journal of medicine · 2012
A 6-month depot formulation of leuprolide acetate is safe and effective in daily clinical practice: a non-interventional prospective study in 1273 patients.
Ulf W Tunn · BMC urology · 2011
Randomized trial of leuprolide versus continuous oral contraceptives in the treatment of endometriosis-associated pelvic pain.
David S Guzick, Li-Shan Huang, Betsy A Broadman, Maureen Nealon, Mark D Hornstein · Fertility and sterility · 2011
Utility of single luteinizing hormone determination 3 h after depot leuprolide in monitoring therapy of gonadotropin-dependent precocious puberty.
Shrikrishna V Acharya, Raju A Gopal, Joe George, Tushar R Bandgar, Padma S Menon, Nalini S Shah · Pituitary · 2009
The efficacy and safety of degarelix: a 12-month, comparative, randomized, open-label, parallel-group phase III study in patients with prostate cancer.
Laurence Klotz, Laurent Boccon-Gibod, Neal D Shore, Cal Andreou, Bo-Eric Persson, Per Cantor, Jens-Kristian Jensen, Tine Kold Olesen, Fritz H Schröder · BJU international · 2008
Comparative efficacy of triptorelin pamoate and leuprolide acetate in men with advanced prostate cancer.
C F Heyns, M-P Simonin, P Grosgurin, R Schall, H C Porchet, South African Triptorelin Study Group · BJU international · 2003
Comparison of leuprolide acetate and triptorelin in assisted reproductive technology cycles: a prospective, randomized study.
Raoul Orvieto, Ram Kerner, Haim Krissi, Jacob Ashkenazi, Zion Ben Rafael, Itai Bar-Hava · Fertility and sterility · 2002
Randomized double-blind study evaluating the efficacy on uterine fibroids shrinkage and on intra-operative blood loss of different length of leuprolide acetate depot treatment before myomectomy.
V M Jasonni, R D'Anna, A Mancuso, C Caruso, F Corrado, I Leonardi · Acta obstetricia et gynecologica Scandinavica · 2001
Leuprolide acetate depot and hormonal add-back in endometriosis: a 12-month study. Lupron Add-Back Study Group.
M D Hornstein, E S Surrey, G W Weisberg, L A Casino · Obstetrics and gynecology · 1998
Absence of a dose-response effect of leuprolide acetate on leiomyomata uteri size.
R J Kiltz, J Rutgers, J Phillips, M L Murugesapillai, O A Kletzky · Fertility and sterility · 1994
Gonadotropin-releasing hormone agonist use before hysterectomy.
T G Stovall, R L Summit, S A Washburn, F W Ling · American journal of obstetrics and gynecology · 1994
Role of leuprolide acetate depot in hysteroscopic surgery: a controlled study.
A Perino, N Chianchiano, M Petronio, E Cittadini · Fertility and sterility · 1993
A controlled trial of leuprolide with and without flutamide in prostatic carcinoma.
E D Crawford, M A Eisenberger, D G McLeod, J T Spaulding, R Benson, F A Dorr, B A Blumenstein, M A Davis, P J Goodman · The New England journal of medicine · 1989
Single-dose pharmacokinetics of leuprolide in humans following intravenous and subcutaneous administration.
L T Sennello, R A Finley, S Y Chu, C Jagst, D Max, D E Rollins, K G Tolman · Journal of pharmaceutical sciences · 1986